Porous PEEK™ Technology

Manufactured through a proprietary extrusion process, the first-of-its-kind porous architecture is designed to promote bone in-growth¹ while maintaining the biomechanical¹ and imaging properties of PEEK.

Porous PEEK

Advanced Materials Science®

Adhering to the three core principles of Advanced Materials Science—Surface, Structure, and Imaging—NuVasive has pioneered design and manufacturing methods that combine the inherent benefits of porosity with the advantageous material properties of PEEK to create implants intelligently designed for fusion.

Patients

Significantly better outcomes than structural allograft or smooth PEEK implants as early as 6 weeks as demonstrated in animal models.²

Surgeons

Porous PEEK implants have demonstrated >3x the integration strength of smooth, solid PEEK implants as demonstrated in animal models.³

Hospitals

Porous PEEK avoids the need for in-hospital sterilization through sterile packaged implants.

Porosity drives in-growth

The proprietary porous surface technology featured in porous PEEK implants has been shown to elicit a biological response in preclinical animal models,¹ effectively reducing fibrous tissue encapsulation observed in both smooth PEEK and smooth

titanium implants.¹

Porosity drives integration strength

Interconnected porous PEEK scaffold supports strong mechanical interlock through bone in-growth in preclinical animal models. ^1-2

Porosity drives outcomes

Significant improvements in clinical outcomes reported with porous PEEK vs. smooth PEEK and structural allograft in anterior cervical discectomy and fusion as early as 6 weeks.³

Durable porous structure

Porous PEEK maintains high porosity under conditions that replicate anatomic loading and resists abrasion damage and delamination under impacted insertion.^4,5

Clear imaging for postoperative confirmation of fusion

Created with imaging in mind, Porous PEEK leverages the radiolucent properties of PEEK to enable radiographic visualization on a variety of imaging modalities.

This provides surgeons with the ability to assess placement of the implant intraoperatively and confirm fusion postoperatively.

Porous PEEK portfolio

Cohere TLIF-A

Cohere TLIF-O

Cohere XLIF

Cohere Cervical

Coalesce TLIF/PLIF

Coalesce TLIF

^{For important product safety information on each of the implants in the Porous PEEK portfolio, including, but not limited to, indications for use, contraindications, warnings, precautions, and potential adverse effects, please see the product specific Instructions for Use which can be found at nuvasive.com/eifu.

1. Evans NT, Torstrick FB, Lee CS, et al. High-strength, surface-porous polyether-ether-ketone for load-bearing orthopedic implants. Acta Biomater 2015;13:159-67.

2. Hill CP and Strenge KB. Early clinical outcomes comparing porous PEEK, smooth PEEK, and structural allograft interbody devices for anterior cervical discectomy and fusion. J Spine Neurosurg 2019;8(1):1-7i.

3. Torstrick FB, Lin ASP, Potter D, et al. Porous PEEK improves the bone-implant interface compared to plasma-sprayed titanium coating on PEEK. Biomaterials 2018;185:106-16.

4. Cheng A, Cohen DJ, Boyan BD, et al. Laser-sintered constructs with bio-inspired porosity and surface micro/nano-roughness enhance mesenchymal stem cell differentiation and matrix mineralization in vitro. Calcif Tissue Int 2016;99:625-37.

5. Evans NT, Torstrick FB, Lee CS, et al. High strength surface-porous polyether-ether-ketone for load bearing applications. Acta Biomater 2015;13:159-67.}