Porous PEEK™ Technology

Manufactured through a proprietary extrusion process, the first-of-its-kind porous architecture is designed to promote bone in-growth1 while maintaining the biomechanical1 and imaging properties of PEEK.

Porous PEEK

Advanced Materials Science

Adhering to the three core principles of Advanced Materials Science—Surface, Structure, and Imaging—NuVasive has pioneered design and manufacturing methods that combine the inherent benefits of porosity with the advantageous material properties of PEEK to create implants intelligently designed for fusion.

Porous surface designed to participate in fusion

Porosity elicits a significantly stronger osteogenic response at the cellular level compared to roughened or nano-roughened surfaces2-5 on their own.

Porous endplate design promotes new bone on-growth and in-growth,1 leading to greater integration strength than smooth PEEK.6,7

The increased surface area and wicking capability of the porous surface improves blood to implant contact compared with traditional interbody implants.1

Watch the Porous PEEK wicking video

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Durable structure mimics the architecture and stiffness of bone

Porous PEEK is manufactured through a proprietary extrusion process, which results in a unified porous-to-solid structure.

Porous PEEK maintains high porosity under conditions that replicate anatomic loading and resists abrasion damage and delamination under impacted insertion.9,10

With a stiffness similar to bone, Porous PEEK implants reduce stress shielding and risk of subsidence, compared with conventional metal implants.1

Clear imaging for postoperative confirmation of fusion

Created with imaging in mind, Porous PEEK leverages the radiolucent properties of PEEK to enable radiographic visualization on a variety of imaging modalities.

This provides surgeons with the ability to assess placement of the implant intraoperatively and confirm fusion postoperatively.

Fluoros

1 Preclinical data on file; data may not be representative of clinical results. 2 Cheng A, Humayun A, Cohen DJ, et al. Additively manufactured 3d porous ti-6al-4v constructs mimic trabecular bone structure and regulate osteoblast proliferation, differentiation and local factor production in a porosity and surface roughness dependent manner. Biofabrication 2014;6:045007. 3 Cheng A, Humayun A, Boyan BD, et al. Enhanced osteoblast response to porosity and resolution of additively manufactured ti-6al-4v constructs with trabeculae-inspired porosity. 3D Print Addit Manuf 2016;3:10-21. 4 Cheng A, Cohen DJ, Kahn A, et al. Laser sintered porous ti-6al-4v implants stimulate vertical bone growth. Ann Biomed Eng 2017;45:2025-35. 5 Cheng A, Cohen DJ, Boyan BD, et al. Laser-sintered constructs with bio-inspired porosity and surface micro/nano-roughness enhance mesenchymal stem cell differentiation and matrix mineralization in vitro. Calcif Tissue Int 2016;99:625-37. 6 Torstrick FB, Lin ASP, Gall K, et al. Porous PEEK improves the bone-implant interface compared to plasma-sprayed titanium coating in PEEK: in vitro and in vivo analysis. Transactions of the 2017 Annual Meeting of the ORS, San Diego, CA; Poster 0835. 7 Torstrick FB, Evans NT, Stevens HY, et al. Do surface porosity and pore size influence mechanical properties and cellular response to PEEK? Clin Orthop Relat Res 2016;474(11):2373-83. 8 Evans NT, Torstrick FB, Lee CS, et al. High strength surface-porous polyether-ether-ketone for load bearing applications. Acta Biomater 2015;13:159-67. 9 Evans NT, Torstrick FB, Safranski DL, et al. Local deformation behavior of surface porous polyether-ether-ketone. J Mech Behav Biomed Mater 2017;65:522-32. 10 Torstrick FB, Klosterhoff BS, Westerlund LE, et al. Impaction durability of porous poly-ether-ketone (PEEK) and titanium-coated PEEK interbody fusion devices. Spine J 2018;18(5):857-65.