NuVasive Biologics
The NuVasive Biologics portfolio includes procedurally integrated allogeneic bone graft substitutes and extenders, and synthetic ceramic bone graft substitutes intended to promote bone fusion.
The NuVasive Biologics portfolio includes procedurally integrated allogeneic bone graft substitutes and extenders, and synthetic ceramic bone graft substitutes intended to promote bone fusion.
Fusion is primarily performed to eliminate the pain often caused by abnormal motion of the vertebrae. Fusion is a surgical procedure in which one or more of the vertebrae of the spine are joined together (fused) so that motion no longer occurs between them.
Bone grafting is a surgical technique that involves implanting a bone substitute or extender to help the body achieve spinal fusion. The three essential biologic mechanisms involved in complete bone grafts include osteoconduction (a scaffold for the reparative growth of the natural bone), osteoinduction (signals encouraging undifferentiated cells to become active osteoblasts), and osteogenesis (living bone cells in the graft material contribute to bone remodeling).
1. As of date of publication, March 2017; data on file. 2. Polini A, Pisignano D, Parodi M, et al. Osteoinduction of human mesenchymal stem cells by bioactive composite scaffolds without supplemental osteogenic growth factors. PLoS ONE 2011;6(10):1-8. 3. Duan R, Barbieri D, Luo X, et al. Variation of the bone forming ability with the physicochemical properties of calcium phosphate bone substitutes. Biomater Sci 2018;6:136-45.